You are on a mission. You must enter an enemy country and do as much damage as possible. This is a long term mission, and the goal is to be effective, whether right away or years later. If you find conditions are favorable, your orders allow you to act quickly, but you also have the option of forming a “sleeper cell”, where you can lay low and wait for the best time to strike.

The country’s border is supposed to be closed, but it really isn’t. You can get across readily, but where do you go once inside, and how quickly do you act? How strong is the resistance — are you welcomed or do you encounter stiff opposition? Can you go wherever you want, or are you limited in your destination? Have you been given specific orders from your home government, or have you been told to decide for yourself how to wreak havoc?

This situation is likely happening in real time in the U.S. The migration environment we’ve created has opened the door to great risk.

Speculation is running wild in this country. Have we just let in a large number of people from foreign countries into the U.S. who intend us harm, or are they all harmless migrants just looking for a new life here? Recently, the composition of the migrant population coming across our borders has shifted from being mostly from Mexico to originating from typically less friendly countries like China, Iran, Egypt, and Venezuela. They may simply be fleeing their home countries, but some may also have been sent on a mission — we simply don’t know how many are coming for possible offensive purposes. We do know that record numbers on terrorist watch lists have been caught, but we also know that many of those coming across the border are “got-aways”, never caught or processed in any significant way. We’ve seen how sleeper cells work in the past, and we could be setting ourselves up for new ones to act some months or years into the future. We are also seeing an increase in crime from some who cross our border and act spontaneously. Yes, most are simply refugees from their home countries and are coming to where they believe they can live better lives. Our problem is that we’ve created a situation where we simply don’t know the background of a large portion of the people pouring across our border. Whether or not we are doing a good thing by letting so many into the country, there is no doubt that we are significantly increasing risk at the same time.

What we’ve done recently is make the environment conducive to illegal border crossings. With the help of human traffickers and cartels, migrants from all over the world are coming here. We could change that environment once we develop the political will to do so. Migration follows the path of least resistance and seeks the most welcoming environment.

You can’t do much about the migrant situation in the United States — those you help vote into office will — but there is another, much more personal risk that you can deal with. Cancer, even if you don’t have a diagnosis of the disease, is a constant danger. Most of us develop cancer cells in our bodies multiple times during our lives, but that doesn’t mean that we will have cancer. Environment is key, both to promoting cancer cells to develop, and to successfully eliminating them.

Your very own sleeper cells
Cancer has two modes. The first is active, where the cells are rapidly multiplying and consuming resources voraciously. The second mode is dormancy, where the cancer cells hunker down and wait, perhaps for years, before switching to an active state. In dormancy, they are hard for the body to detect, but they aren’t doing any damage while dormant. What wakes them up? They are waiting for a welcoming environment — welcoming for cancer, not you: stress, inflammation, a weakened immune system are conditions cancer loves. Generally, chronic bad health is great for cancer.

Once a tumor has developed, cancer now has a major base of operation from which to launch its migrants. Some cells will cross the border of the tumor colony, using the body’s circulatory systems (bloodstream and lymphatic systems) to travel. Away from their relatively safe home colony, they will either activate or go dormant. Which will it be?

Take the fork in the road
Researchers are trying to learn the answer to that question, because a sleeper cell is greatly preferred over an active cancer cell. Published in Nature Cancer, a research team with members from the German Cancer Research Center and from Heidelberg University in Germany tested various cancer cell lines for differences between activity and dormancy. In each case, there was no genetic difference. In fact they only found one difference, which was the level of “methylation” found in the DNA of the cells. Methylation puts a sort of marker on DNA, which tells which portions of the DNA will be actively utilized, and which will be ignored so long as the markers remain in place. In other words, these markers tell cells which portion of their total DNA code to use right now. The researchers found that more methylation resulted in rapid activity and growth of the cancer cells because they were not responding to Wnt (Wingless-related integration site) signaling factors which are meant to control cell growth and differentiation (specialization) of cells. The extra methylation shut down the responsiveness of the cells to normal growth regulation. Cell lines with fewer of these genetic code expression-limiting markers were more likely to go dormant.

The researchers saw that this methylation had already occurred before the cancer cells “decided” whether to activate or not. The choice was predetermined, but by what? To understand this, we have to consider epigenetics, which is genetic expression “on top of” the genetic code. Epigenetic expression is vital to our everyday survival: if our cells had to stay with the same genetic expression regardless of what was going on around us, we would be unable to adapt to changing circumstances and be as extinct as the dinosaurs, which apparently couldn’t adapt to broad changes in their environment. Epigenetics give cells the ability to respond to environmental pressure by trying different code sequences to see which ones allow them to manage their immediate environmental conditions. Epigenetics are the main reason cancer gets started in the first place, as cells which are responding to a harsh, unfavorable environment try different ways of coping to see what gives them better ability to survive and even thrive under the current conditions.

Going down
Cancer cells therefore start as normal cells which change their epigenetic responses. Cancer cells often take a series of downward steps to reach full-blown cancer. These steps are single epigenetic responses which add up to cancer. We often use the term “pre-cancerous”: that term would be meaningless if the cells had not changed is some ways from normal but were not cancerous yet. The transition steps make the cells hardier and less responsive to their harsh surroundings.

The researchers in this study simply verified a continuation of the epigenetics common to all cells. Cells migrating from the tumor had methylated markers which were their orders after they crossed the border as to whether to activate or be sleeper cells. But such markers were set based on environment. The research also showed, “once committed to a dormant fate, (a dormant cell) requires dramatic events to be awakened.” What are such events? It would be sensible to conclude, since we are talking about epigenetic responses to cell environment, that these would be negative events causing a harsh environment that would provoke the cells to change their genetic expression to better cope. That would be a correct conclusion.

According to researchers at the Cold Spring Harbor Laboratory in New York, who published the results of an animal study in Science, cancer cells can remain in the dormant state for years, even decades. They conducted an animal study where they caused sustained lung inflammation from tobacco smoke exposure, and they saw that disseminated, dormant cancer cells switched to aggressively growing metastases. The sustained inflammation caused formation of neutrophil extracellular traps (NETs) which were required for awakening dormant cancer. In their words, “Mechanistic analysis revealed that two NET-associated proteases, neutrophil elastase and matrix metalloproteinase 9, sequentially cleaved laminin. The proteolytically remodeled laminin induced proliferation of dormant cancer cells by activating integrin alpha-3beta-1 signaling. Antibodies against NET-remodeled laminin prevented awakening of dormant cells.” They then noted evidence from human observation that elevated blood levels of C-reactive protein (CRP), which is a general marker of chronic inflammation, correlates with a lowered disease-free survival rate. This also suggests that chronic inflammation is a trigger to turn on dormant cancer cells.

In another study, which was published in Science Transitional Medicine, researchers linked cancer awakening to chronic stress. In an animal study they cited a mechanism where stress hormones (they tested cortisol, epinephrine, norepinephrine, and serotonin) activated neutrophils, which are immune system cells that then produced inflammation-inducing proteins called S100A8 and S100A9. These then altered certain lipids (fats) that accumulated in the neutrophils, which then interacted with the dormant cancer cells, activating them. So this study cites stress as a cause of cancer cell activation. But the stress led to inflammation, so are we talking about the same trigger for cancer, just in different forms?

It’s basically the same trigger. Stress and inflammation fit together like a hand does a glove. Toxins, low sleep, lack of exercise, poor diet, and particularly negative thought patterns all result in stress and system-wide chronic inflammation. That’s why CRP was used as an indicator, because it is a general inflammation marker that usually suggests high level of stress when elevated. Since the brain controls the body, and it is the source of most stress, thoughts — both conscious and subconscious — are the most important factors to deal with to reduce inflammation.

What the world needs now…
The greatest thoughts are those of love — loving and being loved. Giving love is a choice — a purposeful choice. Receiving love requires trust. Giving and receiving love is the highest purpose in life. Purpose outside of love is meaningless. If your purpose is to just be happy, or to accumulate wealth or possessions, it will fail you. If you do not believe that your life has meaning and value coming from beyond yourself, you can’t have a purpose. Purpose grounded in love is your highest possible thought, and we are seeing that will reflect back to your physical health as well. Your cells are listening — what are they hearing?

 

Dr. Nemec’s Review

What causes dormant cancer cells to become active and start growing and metastasizing? Stress and inflammation.

What causes inflammation?
Stress! The stress of thinking, the stress of the mind, and the stress of physical factors — most importantly, the stress of what you eat, drink, and breathe.

What causes stress?
The thoughts, the perceptions, the attitudes and opinions that were made early in life. These were stored in the subconscious mind, written as a computer program which is written on the hard drive of your computer — your brain. These are written into brain tissue with growing neural pathways. These are no longer thoughts alone, but neurological brain body pathways.

Stress is also caused by the physical factors that you participate in every day. What you eat, what you drink, what you breathe — along with what you think — these become the stressors that will either make disease like cancer become dormant, or become active.

The power of understanding this research is knowing that stress and chronic inflammation make normal cells become cancer cells — or if the cancer cells are already present, the stress and chronic inflammation cause them to become active and mobilized, even if they’ve been quiet and dormant for many years. This is why we have many patients contact us at Revolution New Medicine that either never get rid of their cancer with conventional treatment or it just keeps coming back six months later or six years later. What controls whether it comes back or not?

You do!

You are the master controller of your environment of 100 trillion cells. You can choose what you think about consciously. You can choose what you eat, what you drink, and to some extent what you breathe. You can choose the people you spend time with paying attention to their level of stress and inflammation because you become the environment you remain in. You either eventually change them or they eventually change you.

What you cannot control could very well be the straw that breaks the camel’s back. What is the one factor that you cannot control? What is the one factor that you are not even aware of that controls up to 95% of your cellular function? The answer is what is stored in your subconscious mind, written as a neural program in your brain communicating with your body. Remember, subconscious is below conscious awareness. This programming started early in life, age 0 to six. You were programmed by your early environment, which you knew nothing of in those formative years.

How can you know the unknowable? How can you know what’s written as a program in the subconscious mind? To know this requires some physical measurement or analysis for confirmation, not only to know the imbalances there, but also to confirm once the imbalances are gone.

One of your greatest fears
If you’ve had cancer ever in your life, your greatest fear is that it will return. You live a life on the edge, always in fear, hoping that you’ll stay healthy.

Why does cancer return?
According to these studies it never left. It just temporarily went dormant, waiting for the opportunity to turn back on and continue growing and spreading.

Does this mean you’re never in control? Does this mean you’re at the mercy of time and chance? Absolutely not.

For the last 40 years at Revolution New Medicine, we have worked with patients from all across the world with our unique protocol to address subconscious programming, conscious programming, and all of the physical factors that cause stress and inflammation at the cellular level. This stress and inflammation then causes either cancer stem cell formation or reactivation of dormant cancer stem cells.

So you do not have to live in fear. Life is not time and chance — instead you can take control and live in peace.

What the world needs now is Love manifesting through the person who is Peace.
Peace is not an emotion. It is a person, and if you have a relationship with this person, peace fills every part of your being. Dormant cancer stem cells can either remain dormant indefinitely or revert back to normal stem cells when this peace fills every part of your being.

Words from the Master of peace:
My peace I give to you, not like the false peace that emotion gives.

(1) Moritz Jakab, Ki Hong Lee, Alexey Uvarovskii, Svetlana Ovchinnikova, Shubhada R. Kulkarni, Sevinç Jakab, Till Rostalski, Carleen Spegg, Simon Anders, Hellmut G. Augustin. Lung endothelium exploits susceptible tumor cell states to instruct metastatic latency. Nature Cancer, 2024; DOI: 10.1038/s43018-023-00716-7

(2) Albrengues, Jean et al. “Neutrophil extracellular traps produced during inflammation awaken dormant cancer cells in mice.” Science (New York, N.Y.) vol. 361,6409 (2018): eaao4227. doi:10.1126/science.aao4227, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6777850/

(3) Perego M, Tyurin VA, Tyurina YY, Yellets J, Nacarelli T, Lin C, Nefedova Y, Kossenkov A, Liu Q, Sreedhar S, Pass H, Roth J, Vogl T, Feldser D, Zhang R, Kagan VE, Gabrilovich DI. Reactivation of dormant tumor cells by modified lipids derived from stress-activated neutrophils. Sci Transl Med. 2020 Dec 2;12(572):eabb5817. doi: 10.1126/scitranslmed.abb5817. PMID: 33268511; PMCID: PMC8085740.  https://pubmed.ncbi.nlm.nih.gov/33268511/